Our laboratory focuses on characterizing the inheritance of claw disorders in Holstein cattle.  This work, done with the essential collaboration of Dr. Thomas R. Famula of the UC Davis Animal Science Department, has first concentrated on demonstrating whether particular disorders and traits are indeed heritable, and if so, what is the predicted mode of inheritance. Once a genetic basis to a disorder is confirmed, a concerted search for the molecular defect associated with that disorder or trait can be identified.